WNT3A‐loaded exosomes enable cartilage repair
نویسندگان
چکیده
منابع مشابه
Development and Application of Mesenchymal Stem Cell-derived Exosomes in Cartilage Tissue Repair
Background and Aim: Cartilage defects treatment is one of the most common clinical challenges in orthopedics. The current management techniques help to control symptom and joint function. The cell-free approach to cartilage regeneration through paracrine action has been considered to accelerate and facilitate the healing process and the importance of its urgency in the recovery of military pe...
متن کاملThe Role of Gene Therapy in Cartilage Repair
The key principle of gene delivery to articulations by direct intra-articular injection is to release complementary DNA(cDNA)-encoding medical products that will lead to maintained, endogenous production of the gene products withinthe articulation. In fact, this has been accomplished for both in vivo and ex vivo gene delivery, using several vectors,genes, and cells in some animal models. Some c...
متن کاملChallenging for cartilage repair
Editorial When we look back on the past 15-year history of cartilage repair, it is clear that remarkable progress has been made in this area. There is no doubt that a lot of studies have been carried out on cartilage repair and chondrocytes since Brittebergs' report on ACI in 1994 [1]. I would like to introduce our multi-pronged approach to cartilage repair. After the 1994 report [1], we perfor...
متن کاملFailed Cartilage Repair
The management of traumatic and degenerative cartilage lesions is a known challenge given the limited vascularity and lack of pluripotent cells that contribute to the tissue’s inherently poor regenerative capacity. Many surgical techniques have been described in an effort to palliate symptoms, promote substitute tissue growth, and/or restore normal hyaline cartilage. Surgical failure of these t...
متن کاملArticular Cartilage Repair
This review traces the genealogy of the field of articular cartilage repair from its earliest attempts to its present day vast proliferation of research advances. Prior to the 1980s there was only sporadic efforts to regenerate articular cartilage as it was considered to be incapable of regeneration based on historical dogma. The first flurry of reports documented the use of various cell types ...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Journal of Extracellular Vesicles
سال: 2021
ISSN: 2001-3078,2001-3078
DOI: 10.1002/jev2.12088